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Is Depo-Provera a danger?

By Andrea Smith

Deciding whether to use birth control is a significant and deeply personal choice for a woman. Beyond preventing pregnancy, birth control may also be used to regulate menstrual cycles, reduce anemia, manage endometriosis symptoms, improve skin and lower the risk of developing ovarian and endometrial cancers.

Risks for users of Depo-Provera

While birth control offers benefits, risks also exist. For some users of Pfizer’s injectable drug Depo-Provera (depot medroxyprogesterone acetate), recent research has raised concerns about a potential link to meningioma brain tumors.

Meningioma is a type of brain tumor that develops from the meninges, the thin layers of tissue that cover and protect the brain and spinal cord. It is the most common type of primary brain tumor. Symptoms may include headaches, seizures, vision problems, hearing loss, memory issues, weakness or personality changes –depending on the tumor’s location.

A recent study published in JAMA Neurology suggests prolonged use of Depo-Provera may be associated with an increased relative risk of developing meningioma. Although meningiomas are typically non-cancerous, they can still lead to serious health complications.

Treatment options vary and may include monitoring, surgery, radiation therapy or a combination of approaches, depending on the tumor’s size, growth rate, symptoms and location.

Women seeking compensation for health issues

Legal action is being taken across the country against Pfizer. Depo-Provera is the subject of a growing mass tort, with more than 1,700 cases having been consolidated in a multidistrict litigation (MDL) as of this month. Although Pfizer maintains the drug is safe, the Food and Drug Administration added a meningioma warning to the Depo-Provera label in December 2025. Women involved in the litigation allege injuries linked to long-term use, including brain tumors.

Plaintiffs claim Pfizer failed to adequately warn doctors and patients about the risk of developing meningioma. Under failure-to-warn laws, pharmaceutical manufacturers may be held liable if they do not provide sufficient risk information to allow patients and physicians to make informed decisions. These claims do not assert the drug is defective or fault physicians for prescribing it.

Allegations in lawsuits against Pfizer regarding Depo-Provera include the following:

  • Pfizer was aware or should have been aware of the increased risk of meningiomas associated with prolonged Depo-Provera use.
  • Pfizer failed to adequately warn doctors and patients of potential risks.
  • Some women suffered significant harm, including the need for brain surgery, after continued use without full awareness of the risks.

Plaintiffs are seeking compensation for medical expenses, pain and suffering, lost wages and other damages. Evidence cited includes medical records, prescription histories and expert testimony linking the medication to brain tumors.

Pfizer is the primary defendant. Generic manufacturers named in some of the lawsuits include A-S Medication Solutions, Greenstone LLC, Pharmacia & Upjohn Company LLC, Prasco Laboratories and Preferred Pharmaceuticals Inc.

Statutes of limitations for filing legal claims related to Depo-Provera injuries vary by state. The period to file a lawsuit typically starts when a person is diagnosed with a brain tumor and can reasonably attribute it to the birth control medication.

The litigation is ongoing, with additional cases expected as awareness increases. Individuals who believe their health issues may be linked to Depo-Provera are encouraged to seek qualified legal guidance to explore their options.

About the Author

Andrea Smith is co-managing Partner of Goldstein, Buckley, Cechman, Rice, Purtz, Smith & Smith. She specializes in personal injury and wrongful death cases.

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Being involved in a hit-and-run bicycle accident can be a distressing and overwhelming experience. However, it is important to stay calm and take the necessary steps to protect yourself and ensure your rights are upheld. In this blog post, we will guide you through the necessary actions to take following a hit-and-run bicycle accident in Port Charlotte, Florida. Prioritize Your Safety: The immediate aftermath of a hit-and-run bicycle accident can be chaotic. Ensure your safety by moving out of harm’s way and assessing yourself for any injuries. If you require immediate medical attention, call 911 or ask someone nearby to do so. Gather Information: If you are physically able, try to collect as much information as possible about the incident. Take note of the time, date, and location of the accident. Additionally, try to remember details about the vehicle involved, such as the license plate number, make, model, and color. 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Some injuries may not be immediately apparent, and early detection and treatment are crucial. A medical report will also serve as evidence of your injuries if you decide to pursue compensation. Notify Your Insurance Company: Contact your insurance company to report the hit-and-run accident and provide them with the necessary details. They will guide you through the claims process and help you understand your coverage, including any provisions for uninsured motorists. Cooperate fully with your insurance company and provide them with any documentation or evidence they require. Consult with an Attorney: If you have suffered significant injuries or are facing difficulties with your insurance claim, it is advisable to consult with a personal injury attorney experienced in handling bicycle accidents. They can provide legal guidance, negotiate with insurance companies on your behalf, and help you explore your options for seeking compensation. Explore Other Avenues for Assistance: In addition to insurance claims, you may be eligible for compensation through other sources, such as the Florida Crime Victim Compensation Program or civil lawsuits against the responsible party. An attorney can help you assess your options and pursue the most appropriate course of action. Focus on Recovery: While dealing with the aftermath of a hit-and-run bicycle accident, it’s essential to prioritize your physical and emotional well-being. Follow your healthcare provider’s instructions, attend all necessary appointments, and participate in any recommended rehabilitation or therapy. Engaging in self-care activities and seeking support from loved ones can also contribute to your overall recovery. Spread Awareness: One way to turn a negative experience into a positive outcome is by spreading awareness about hit-and-run accidents and advocating for safer cycling conditions. Share your story on social media, participate in local community events, and support organizations working to improve cyclist safety. By raising awareness, you can help prevent future accidents and provide support to other victims. Handling a hit-and-run bicycle accident in Port Charlotte, Florida, requires patience, determination, and a thorough understanding of the necessary steps to protect your rights. By staying organized, seeking appropriate legal assistance, and focusing on your recovery, you can navigate the process more effectively and increase your chances of obtaining the compensation you deserve. Remember, you are not alone, and there are resources and support available to assist you through this challenging time. At Goldstein, Buckley, Cechman, Rice & Purtz, P.A., we understand the complexities and challenges involved in hit-and-run bicycle accident cases in Port Charlotte, Florida. Our experienced team of personal injury attorneys can provide valuable assistance and guidance throughout the entire process. Here’s how we can help: Legal Expertise: We have a deep understanding of Florida’s laws related to hit-and-run accidents and personal injury claims. Our team has extensive experience in handling bicycle accident cases, including those involving hit-and-run incidents. We stay up-to-date with the latest legal developments to provide our clients with the most effective representation possible. Investigation and Evidence Gathering: In hit-and-run bicycle accidents, gathering evidence is crucial. We have the resources and expertise to conduct a thorough investigation into the incident. Our team can gather witness statements, review accident reports, collect video surveillance footage, and work with accident reconstruction experts, if necessary, to build a strong case on your behalf. Communication with Insurance Companies: Dealing with insurance companies can be challenging, especially in hit-and-run cases where the responsible party is unknown. We can handle all communication with insurance companies, ensuring that your rights are protected and that you receive fair compensation for your injuries, property damage, and other losses. Maximizing Compensation: Our goal is to help you obtain maximum compensation for your damages. We will carefully evaluate your case, including your medical expenses, lost wages, pain and suffering, and other related losses. With our expertise, we can accurately assess the value of your claim and negotiate with insurance companies or, if necessary, take your case to court to fight for your rights. Assisting with Legal Proceedings: If the responsible party is identified or located, we will guide you through the legal process, including filing a lawsuit if necessary. Our experienced attorneys will represent your interests, prepare your case for trial, and advocate on your behalf to seek the compensation you deserve. Support and Guidance: We understand the emotional toll that hit-and-run bicycle accidents can have on victims. Throughout the process, we provide compassionate support and guidance, answering your questions, addressing your concerns, and keeping you informed about the progress of your case. Our team is dedicated to ensuring you feel supported and confident in pursuing your legal rights. Goldstein, Buckley, Cechman, Rice & Purtz, P.A. has the experience, knowledge, and dedication to assist you with hit-and-run bicycle accident cases in Port Charlotte, Florida. We are committed to fighting for your rights, seeking justice, and helping you obtain the compensation you deserve. Contact us today for a consultation and let us be your trusted legal advocates during this challenging time.

How Do Comparative Fault Rules Apply to Motorcycle Accident Cases?

If you've been in a motorcycle crash in Fort Myers, FL, comparative fault rules will have an effect on your final award if you were partly to blame. Talk to a motorcycle accident lawyer as soon as you can to make sure you know what your options are and to protect yourself from any unfair accusations of fault. Comparative Fault In Fort Myers, FL Comparative fault divides responsibility for an accident, assigning percentages of fault to everyone involved (when justified). The idea is to make sure compensation matches the degree of responsibility each person holds, and your final compensation is usually cut by the same percentage as your fault. So, for example, if you were hit by a car that turned without looking when you had the right of way, they'd be primarily to blame. However, if you were also speeding at the time, you might be assigned 10% of the fault on the theory that you might have avoided the accident if you hadn't been speeding. That means you'd be able to recover 90% of your losses and damages. Florida follows a modified comparative negligence rule, which means you're able to recover so long as your fault is 50% or less. If you're more than 50% at fault, you can't recover anything at all. Florida used to have a pure comparative negligence approach, where you could recover at least a little bit even if you were 99% at fault, but since 2023 that's no longer the case. How Fault Is Determined Fault is about who failed to exercise reasonable care under any given circumstance, and in a motorcycle accident, it can be hard for the cyclist to get a fair hearing. Many people assume that motorcyclists are reckless by nature, so having a lawyer is particularly important. You'll want the help of someone with experience in the legal system and an understanding of the bias that cyclists face. Motorcyclists frequently encounter situations where a car or truck driver's inattention is the primary cause of the accident, but rider errors such as speeding or improper cornering can be an issue; and the insurance companies typically look hard for any evidence of fault on the part of the rider. Other Ways Your Award Can Be Affected Florida law also allows insurance companies to argue that your choice not to wear a helmet worsened certain types of injuries, even if you were actually following all state laws and even if you didn't contribute to the accident itself. Riders over 21 who have at least $10,000 in medical insurance coverage may legally ride without a helmet, but if you suffer head trauma, the defense may claim that proper headgear would have reduced the severity of your injuries. They will then argue that they shouldn't have to pay for all your medical bills. Talk to a Motorcycle Accident Lawyer If you've been in an accident, give us a call at Goldstein, Buckley, Cechman, Rice, Purtz, Smith & Smith, P.A. in Fort Myers, FL at (239) 441-2009 for a no-obligation discussion about your rights. You can also talk with us at our offices in Cape Coral, Naples, Lehigh Acres, or Port Charlotte.

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